Mesenchymal hamartoma in liver (Pediatrics)

Mesenchymal hamartoma

  • Mesenchymal hamartoma is the second most common benign liver mass in children after vascular tumors.
  • Most are discovered before 5 years of age
  • Boys > Girls
  • Diagnosed on prenatal ultrasound
  • Generally considered a congenital lesion related to a developmental anomaly
  • Most common clinical presentation : Painless abdominal distension with normal AFP level
  • The mass may be pedunculated and attached to the inferior surface of the liver
  • Imaging finding
    • USG
      • Multicystic, heterogeneous masses with septa of variable thickness
      • When the cysts are tiny – mimics a solid lesion
      • Gelatinous contents or hemorrhage ; can be seen as hypoechos in the cyst
    • CT
      • Complex cystic masses
      • Septations and solid components are enhanced
    • MRI
      • Cystic regions are hypointense on T1WI and hyperintense on T2WI (of coursely)
      • Other portions show variable signal depending on components

Mesenchymal hamartoma
Case from Radiology Illustrated: Pediatric Radiology,  ‎Springer; 2014th edition
Mesenchymal hamartoma in a 9-month-old boy.
( a ) Plain abdominal X-ray shows huge soft-tissue opacity in right upper abdomen.
( b ) Longitudinal US image of liver shows huge and multilobulated cystic mass originated from the liver.
( c ) Contrastenhanced abdominal CT also demonstrates multilobulated cystic mass from the liver
large multiloculated mass with variable septa and cystic spaces or mixed solid and cystic tumor
large multiloculated mass with variable septa and cystic spaces or mixed solid and cystic tumor
Gross feature of mesenchymal hamartoma
Gross feature of mesenchymal hamartoma
Differential diagnosis of liver tumor
From Caffey’s Pediatric Diagnostic Imaging, 12e

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