- Second most common histologic type (10~15%)
- Higher incidence of multifocality, multicentricity, and bilaterality
- E-cadherin negative
- Indian file appearance
- Common cause of missed or delayed diagnosis
- Not common desmoplastic reaction ➨ US, MR is better than MG
- Larger at diagnosis than IDC
- Imaging finding
- MG : Spiculated mass (m/c), isolated architectural distortion, calcification rare
- US : Irregular hypoechoic mass, marked posterior shadowing
An 59 year old woman presented with large right breast mass
![invasive lobular carcinoma](https://q-radiology.com/wp-content/uploads/2022/10/image-137.png)
![invasive lobular carcinoma](https://q-radiology.com/wp-content/uploads/2022/10/image-136-1024x452.png)
![invasive lobular carcinoma](https://q-radiology.com/wp-content/uploads/2022/10/image-138-1024x682.png)
![](https://q-radiology.com/wp-content/uploads/2022/10/image-139-1024x681.png)
Note that invasive lobular carcinoma has tendency of multifocality, multicentricity, and bilaterality
![indian file appearance in invasive lobular carcinoma](https://q-radiology.com/wp-content/uploads/2022/10/image-140.png)